@hopeful33250 Sure, Teresa. The nerve/muscle issue is not difficult to understand. Amyloidosis is a matter of genetically mis-formed protein particles. Form many people, this process begins at conception. For others, it is available, beginning at conception, but does not operate until triggered by something like radon, 2-4D, 2-4-5T, Roundup, radiation from nuclear testing, or some chemical. There are many triggers to actually start the protein to mis-form. In any case, the pieces of protein, usually produced by the liver, float around the body to do their necessary work. But the mis-formed pieces create more mis-formed pieces in the liver, but should be filtered out by the body, especially the kidneys. But the kidneys get plugged, so the pieces then deposit themselves in any tissue in the body. Nerve, muscle, bone, fat, whatever. Each mutation has its special place to deposit itself. Just like me cat has a special place it likes to sleep at night. Anyway, some forms are fibrilogenic, meaning they get into a tissue, then make little tubes of water called fibrils. These fibrils push the cells of the nerves and/or muscles apart, interrupting their ability to work. The muscles get weaker, not able to tense up. The sensori-motor nerves cannot pass the signals from the brain. So the heart cannot beat, the lungs can not breathe properly. The skin tissue is not able to reproduce itself smoothly and colored properly. Some dead protein is deposited in the bottom of the cerebellum, and is called Alzheimers. My form of dementia is deposited in the top of the cerebellum and is called cerebral cortex Amyloidosis. It all stems from mis-folded protein particles which float around the body. They are like several children's jacks laid out to make a layer of them, then another layer on top of the first can be laid down, but will only fit a certain way, and another, etc., until it makes a chain of protein. If they do not fit, one layer on another, the layers die, and form fibrils. So you get a test, developed by Bindings of UK, called "Serum FreeLiteChain@ Assay, and do a 24-hour Proteinuria assay, to discover whether your kidneys are filtering out all the misfolded or unused protein. If the sFLC number is 1.8 mg/dl, or the 24-hr Proteinuria is 0.500 G/24 hour, you have some form of Amyloidosis, and must be tested to determine the mutation of your over-abundant protein. I know this is a lot, but maybe it will help.