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Other causes of failed PEth test for alcohol abuse?
Mental Health | Last Active: 6 days ago | Replies (430)Comment receiving replies
Please get this article in front of someone at the monitoring program: Viel et al. Int J Biochem (2012). The article shows that PEth levels are markedly elevated in inflammatory conditions where Protein Kinase C-alpha (PKC-a) enzymes are overactive. MS, for example, is one such condition.
PKC-a preferentially phosphorylates the amino acid, threonine. Threonine contains an ethanol component or “moiety.” Is it not possible that phosphorylation of amino acids that contain ethanol could produce something that at least looks or acts like PEth? I think it’s very possible if not likely.
I’ve raised this issue with the principal marketer of the PEth test. No response. I think these folks are making bank on a shockingly poorly vetted test. They have no clue as to what can potentially affect these results....biochemistry is complicated! And remember this test is not FDA-approved....precisely because so little is known about it.
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Hello! I know this is an old message thread but I would be very interested in more information on this. My boyfriend had what we KNOW is a false positive PEth test and this is affecting his security clearance at his job. We are trying to fight this and they are requesting documentation of other instances of false PEth tests. He's on a number of prescriptions for diabetes so I'm currently researching if this is a possibility as well and his liver is routinely monitored by his doctor due to random elevated enzyme levels. I'm hoping you've continued to research this and have some updated information. This has greatly affected his job and put his very career in jeopardy even though his EtG was negative. Would appreciate any guidance you can provide.