Hi Erika, I have been taking 10 mg of Celexa plus 1 mg of Clonazepam to help with anxiety since 2010. I could never take more than 10 mg because it exacerbated my restless leg syndrome which is very severe. I suffered from spinal stenosis also causing me great pain in my neck area and was given Gabapentin 900 mg per day. I had an ablation procedure finally which eliminated my pain but I continue to take the Gabapentin once I realized it worked for restless leg syndrome and my severe symptoms return if I stop it. This pandemic has caused my chronic depression to ramp up. I tried to go up to 20 mg of Celexa but my legs flared up. So I cut back to 15 mg which I can tolerate and has helped but I battle keeping the sadness at bay. That is why my friend with chronic depression recommended I try Trintellix also. I am very reluctant to tamper with my Celexa because I have suffered so much my whole life with restless legs. My doctor is willing to work with me on the antidepressant but will not increase my Gabapentin which I don’t want to do either. So that prompted my question regarding Trintellix and restless legs. Thanks so much for your inquiry.