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Anyone have nausea with Trintellix?

Depression & Anxiety | Last Active: Aug 9 12:12pm | Replies (69)
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@heidi1346

I am extremely nauscious from trintellix and have an upset stomach. I believe the Nausia goes away but does the upset stomach go away

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Replies to "I am extremely nauscious from trintellix and have an upset stomach. I believe the Nausia goes..."
Colleen Young, Connect Director | @colleenyoung | Jan 17, 2021

Hi @heidi1346 and welcome to Mayo Clinic Connect. It sounds like Trintellix (vortioxetine) is causing several digestive related issues for you, including nausea, upset stomach and severe diarrhea. Nausea is the most common side effect of this drug. I'd like to bring @rossjt @marjou @trip17 @elwooodsdad @petangelkat1 @jeanmnyc @marazion @alamogal635 and @kelster69 into this discussion so they can share their experiences with you.

While we wait for others to join in the discussion, you may also wish to see this discussion thread:
- Switching to Trintellix or Low Dose Naltrexone (LDN) https://connect.mayoclinic.org/discussion/trintillix/

Heidi, have you discussed the side effects you're experiencing with your doctor? How long have you been taking Trintellix? What dosage?

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marjou | @marjou | Jan 18, 2021

I have the nausea and upset stomach at 2.5 mg.

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tink1 | @tink1 | Dec 26, 2021

I have now been on Trintellix for four weeks and the nausea is not going away. I have it every morning and due to working from home and off work for the holidays I can rest it off. However I cannot continue to function like this daily. I am going to discuss alternate choices or go back to Celexa when I see my doctor in New Year

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