I’m 71. I have dysthymia, so I am always experiencing a base line of depression all the time. Can’t remember when I wasn’t depressed. My late mother was also depressed, and there are indications that this is genetic. I am also male, and am a statistical minority. I am pro-active. I’ve had talk therapy, and an assortment of medication. It’s a bit of a crapshoot. I’m seeing my physician/psychiatrist about issues with a new medication. I find being aggressive about managing these issues helps. Anxiety, suicidal ideation, and all the depression issues are unpleasant, and possibly fatal. Dysthymia presents as a constant, low-level depression, and occasionally presents some more intense experiences. Can’t eliminate the problem, but it can be managed.