Thank you I will read the articles. I've read many in the journals. I have hope for this med and realize it may take awhile to integrate into the body . Vasculitis and joint involvement is one of my major symptoms. Neuro is possible. EMG showed nothing last summer, then again the disease was in a remission, though it's never totally gone, symptoms abate to a degree. The drug shows promise . Steroids are not working and Imuran put my liver into acute failure so cannot take it. It did recover thankfully. Thanks again John for your research, all is appreciated and I will post links that are credible as well