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NCCN adds transdermal estradiol to its prostate cancer ADT guidelines
Prostate Cancer | Last Active: 6 hours ago | Replies (23)Comment receiving replies
@climateguy thank you, quite a difference in cost, although I maxed out my $2100 Part D out of pocket with my third bottle of Orgovyx. My MO has me on Prolia, as my Dexa came back showing osteopenia, with a drop in density from a Dexa done 3 years ago.
@jim18 thank you as well. I've already developed a strong A cup in the 4 months I've been on Orgovyx, but if estradiol is as effective as Orgovyx I can deal with that if I don't have to deal with everything else. I see my MO in a couple of weeks, it will be an interesting conversation.
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@carlsbadguy With estradiol you will be able to stop the Prolia at some point since estradiol keeps your bones strong (males convert testosterone to estradiol in fat tissue so ADT breaks this leading to bone loss). Will still need resistance exercises since testosterone is directly involved in maintaining muscle mass.