Yes, I have thoughts. Absolutely! My thoughts to the bone medicines as well as vaccination reactions is that medicine goes where the body needs it and sometimes reactions and inflammatory reactions especially are due to the medicines. Triggering an inflammatory response to where the medicine is doing its job. My first experience with this was when I was treated for hepatitis C in 2001. The injections I did once a week had an unbelievable inflammatory response in my joints. I wished I was dead every Friday night after the injections. But lo and behold after three months, the pain was gone and so was the virus that the injections attacked. After that experience, I went back to receiving vaccinations, and I found that I was especially triggered by the Shingrex vaccine on the first dose. I almost didn’t go back for the second part, but I did and I had zero reaction. What it was was my body mounting a severe immune response because I had dormant measles leftovers living in my joints. After all this, I went returned to getting regular flu vaccinations and I had the same thing happened. I slowly stopped having immune negative immune responses to the flu vaccinations every year. Now I have none so I figured whatever was living dormant in my joints is now gone. I think it is the same with the bone medicines. I had a severe reaction to recast so bad it traumatized me, but it was in the places where I know for sure my bones were compromised because I had cervical spine surgery and my bones fell apart, especially my C5. So my reaction was to that area after I had the class infusion. There are lots of methods to lower immune responses to all these things now so have some conversations with your doctor and your doctor team. Good luck and I hope you go forward with the medicines I have and my bones are a lot stronger because of the medication’s as nasty as they are, LOL!