I have been on Tagrisso 80 mg for 2years & 3 months. The side effects have becoming harder for me to tolerate. I am 81 and that may have something to do with it. I am experiencing bowel problems, facial rash, mouth sores, loss of appetite, fatigue, & nausea and weakness in my legs. My scans have been clear
& I would like to reduce my dosage to 40 mg. I will see my oncologist next week to get the results of my latest CT. I will talk it over with him. Brain MRI next week. My faith in God has gotten me this far , but at my age I would like to have a little more time to enjoy life. God will always be with me!