A high decipher can be caused by other problems

Were any of these things found in the biopsy intraductal, ductal, large cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions). They can make the cancer much more aggressive.

If you have one of those aggressive issues, they can cause the high decipher and can cause reoccurrence.

A 3+4 grows very slowly, normally. The decipher score can make it come back, however. You can have surgery and that way you can have radiation if it comes back. If you have radiation that could take care of it, A 3+4 doesn’t necessarily need ADT. The only reason one would consider it is because of the high decipher.

I had a 3+4 after biopsy but after surgery, I had a 4+3. You never know what your real Gleason score is if you have radiation. A number of people find out they were 4+ fives after surgery, Which could explain the high decipher.