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What can cause ANA titre of 1:2560?

Autoimmune Diseases | Last Active: Jan 12, 2023 | Replies (111)

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Hello @carpe_bean. I have never used this site before & just joined. I just wanted to ask you if you have been tested for Lyme disease & it's co-infections? Ticks rarely carry Lyme disease alone anymore but a multitude of co-infections like Bartonella, Babesia, Ehrlichiosis, Mycoplasma etc. 6 years ago I knew I had Lyme disease & tested the second week after seeing a bullseye rash - but my test came back negative initially. I was not informed at the time that it would take 3-4 weeks for antibodies to form and to retest or how inadequate testing is and the how over 50% of tests will report false negatives. I also didn't realise that only 20% of people will ever notice a tick bite or actually see a bulls eye rash. For years I researched other diagnoses. My symptoms continued and worsened. This may not at all be Lyme disease but it might be something you want to test for. When I first got Lyme my ANA titre was 1:160. It is now 1:2,560; dense, fine & speckled but on secondary testing no sign of Lupus or RA etc. My symptoms ranged from major major bladder & bowel issues, headaches, neck stiffness, terrible insomnia, night sweats, difficulty thinking, cognitive issues, a diagnosis of autonomic nervous system dysfunction, extreme problems with blood pressure, numbness and tingling down left side, pins and needles in my left eye & extreme joint pain. At this point Dr's thought I might have either Lupus or MS. It was then that I remembered that Lyme Disease is known as the Great Imitator and I went back to basics and my initial instinct that this was lyme. I sent my labs to Igenix in the USA - a lyme & coinfection only labaratory and one of the best and I came back with a high positive both both Igenix & CDC standards. Also positive for Babesia, Bartonella & Mycoplasma. Again, your symptoms could be due to other issues but I just thought I would pass this on as your post reminded me a lot of what I went through. I am not sure where you are located. You mentioned German insurance. I have also tested with Armini labs in Germany for viral and lyme infections and they were very good too. I hope this doesn't end up worrying you and that you are already feeling much better. However, if you are not - this might be something you may want to rule out.

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Replies to "Hello @carpe_bean. I have never used this site before & just joined. I just wanted to..."

Hi, I didn't see your post until now. I can't believe how many of your symptoms I've had, right down to the left-side numbness and tingling. So miserable. I'm really sorry you've experienced all this same crap.

I did consider Lyme disease back when I first got sick. I've been bitten by a handful of ticks since moving to Europe, and we live where Lyme is common. Despite that, none of the doctors here even suggested it as AA possible cause of my symptoms. I had to ask an internal specialist to test for it. The test was negative. Another doctor again tested for it, as well as several other tick-bourne disease, and all tests were negative.

At this point (nearly 3 years of being sick), I'm convinced it's a chronic bacterial infection. It's likely something infectious (my hunch and doctors' opinions), and I feel SO much better after antibiotics. Then the symptoms come back. Doctors here say it's absolutely impossible for a bacterial infection to cause elevated ANAs. Agh! So not true.

How were you, treated for Lyme? I assume you took antibiotics? I'd love to know how you're doing now, if you happen to see this post.