← Return to What can cause ANA titre of 1:2560?

Discussion

What can cause ANA titre of 1:2560?

Autoimmune Diseases | Last Active: Jan 12, 2023 | Replies (111)

Comment receiving replies
@kanaazpereira

Welcome to Connect @carpe_bean,

I found this study about the predictive value of antinuclear antibodies (ANA), and thought you might wish to read it:
http://www.sciencedirect.com/science/article/pii/S2211283913000178

I'd also encourage you to view this Mayo Clinic page about ANA results: http://www.mayoclinic.org/tests-procedures/ana-test/details/results/rsc-20344732

Fellow Connect members @hchristopher @lisabeans @taterjoy @brie87144 @jewel8888 @steeldove have all experienced the frustration of not getting a clear diagnosis, and I'm certain they will return with more insight.

@carpe_bean, may I ask if any of your family members have autoimmune disease?

Jump to this post


Replies to "Welcome to Connect @carpe_bean, I found this study about the predictive value of antinuclear antibodies (ANA),..."

Hi @kanaazpereira and thank you,

I can't believe you shared the Science Direct link above. I JUST read this article a couple of weeks ago. It's fantastic! I had read so many articles about ANAs before I found this, too, and none of them really included specifics about high ANAs. Most articles just casually mention that viruses and bacterial infections can cause "elevated ANAs" without going into more detail. According to the article, it sounds like I'm more likely to end up eventually being diagnosed with an autoimmune disease, simply based on statistics.

As far as I know, only two family members had/have autoimmune diseases. My maternal grandmother died of SLE with complications from nephritis when she was 39, my age. And I have a paternal first cousin with RA. My mom was adopted so I have very little family medical history for her side of the family beyond my grandmother.
Interestingly enough, I just had an appt with a rheumatologist this week and she said she's sure I DON'T have any rheumatic autoimmune diseases. She suspects autoimmune hepatitis strictly based on my ANAs and chronically elevated liver enzymes - GgT, ALT, and AST have been high since I got sick in January. She recommended I see a gastroenterologist. Apparently rheumatologists don't treat all autoimmune diseases? Gastroenterologists are booked out three months here, so I guess for now, it's back to the waiting game. In the meantime, I plan to head over to find a forum for Connect members with autoimmune hepatitis and follow their thread.