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Leg cramps at night

Breast Cancer | Last Active: Oct 6 4:10pm | Replies (51)

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I started Tamoxifen about 3 months ago and I also am having leg cramps that wake me up at night and sometimes happen in the daytime. My oncology team recommended I tried taking 1/2 of the pill in the AM and 1/2 in PM as well as taking magnesium glycerinate daily. I have been doing that for 2 months now with only occasional relief. I hydrate all day and before bed, but the cramps persist and now I wake up with pain in my right calf every day. It's like a hot soreness. No swelling or bruising though. I am supposed to take Tamoxifen for total of 5 years and really don't want to change to AI's (which is an option for me) because I already have some joint pain before BC and assume it would worsen the joint pain. I am a bit worried that it could be a blood clot/dvt but dreading going in for an ultrasound to find out. Also, I can feel strange sensations in my calfs of sort of a sputtering feeling along with the soreness.
any suggestions?

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Replies to "I started Tamoxifen about 3 months ago and I also am having leg cramps that wake..."

@letsdothis I started Tamoxifen 6 weeks ago and have also noticed leg cramps at night. I’ve been using magnesium lotion and it seems to help. I also take magnesium glycinate. Please go to your doctor, the hot soreness sensation you feel is very concerning for DVT.

@letsdothis I experienced leg cramps and muscle spasms in my calves and feet while on Tamoxifen. The only thing that helped was walking until it felt better. It was very painful. I switched to Letrozole a year ago, and don't get the cramps or spasms anymore.