I was on prednisone for almost 2 years and I developed uncontrollable swelling, high blood pressure, and weight gain. I switched to Kevzara and pain abated but had occasional flare-ups. I have tried going off since I didn’t have major flare-ups. My flare-ups result in being bed-ridden because I lose complete use of my legs ,loss of appetite, and bladder control. Now my pain is back. I’m going back up to Kevzara twice a month. I’m experiencing severe pain, fatigue and depression.