@blackhluk Hi, PNET primary, liver mets, grade 2. Had distal pancreatectomy and liver surgery as 1st treatment 3 years ago, my pancreas is now currently clear, but still have multi focal tumors in my liver. They discontinued Somatuline Depot because my body was no longer uptaking somatostatin and I was having progression, thus also no more dotatate PET scans (nothing shows up on them yet do on MRIs), and I can't do PRRT either. Was told from the getgo this could happen. I had some more progression recently so my treatment was changed to 5 cycles of CAPTEM chemo. Still a little progression going on so I am getting TAE (Trans Arterial Embolization) soon. More than you wanted to know I'm sure ;-), but thx for asking after me! While the injections do have some side effects, they are a pretty easy way to go in my opinion. I hope your treatment goes well for you ,<3!