@john2563 wow sorry you not getting any relief from the Nacala, I’m suprised your not feeling anything being you took 5 injections, I just took my 8th, after I took the first it took couple weeks before I felt anything and moving forward it was slow but definitely felt a improvement, I was talking to another on it and she said I was where i should be on the nucala and it keeps getting better which it has, before I needed my portable oxygen to go food shopping or anything out side my home, I don’t need that no more, have you told your doctor about not feeling anything, I could be wrong but that doesn’t sound right, if your not happy have the doctor change it, it’s our body we know what helps us and what doesn’t so you do what you gotta do, I was only on breztri and Ohtuvayre and it wasn’t enough I had to tell him I want to try another and he started me on the nucala, so speak to your doctor it’s your choice, hope you find something that helps you ❤️