I have had several MOH's done on my face and one on the chest and I always drove myself. I never needed any kind of anxiety medication.
I am scheduled for a CT scan with contrast in November and since I have had hives in the past, I need to premedicate. They also want me to take Benadryl which recommends not driving after so I will stay overnight in Rochester for that.
I had a colonoscopy with general anesthesia done in Rochester. I stayed in hotel across the street from the hospital. After some time in the hospital recovery room, I just walked across the street and stayed the night in the hotel to avoid driving. I told them I was going to do that and they were fine with it.
I drive myself because my potential rides work and I don't want them to take time off from work.