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Curious About Transition From BCG to GEM/DOCE

Bladder Cancer | Last Active: 5 days ago | Replies (16)

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Profile picture for kgborlando @kgborlando

What are the main side effects of the Gem/doce format? I started round 1 of 6 weeks recently. I did the 1 hour Gem introduction in the dr office- laying down-and then the insertion of the doce and I was allowed to leave their office immediately and go home and kept the doce in for the required 1 hour. Does this protocol sound correct? Appreciate any feedback.
For information purposes My BC is low grade stage 0, have had 5 TUBR procedures in last 2.5 years and a 6 week GEM process a year ago. Last TUBR was in March 26 with a GEM 1 hour wash after surgery.

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Replies to "What are the main side effects of the Gem/doce format? I started round 1 of 6..."

@kgborlando
I think my side effects from Gem/Doce may not align with yours since I had suffered from 18 months of active mycobacterium bovis infection from prior BCG. That left my bladder wall pretty sensitive. That said I'll add that Gem/Doce side effects were lessened by laying down during the hour of holding the Gemcitabine. The Docetaxel was not difficult at all for me.

@kgborlando
I had 5 weeks intro, then I'm on 4th maintenance of Gem/Doce. Your protocol is same as mine, except I stay in clinic for the hour with Doce before I drive 1 hour home.
Had my third cystoscopy last Thursday. Clear, but have to continue 4-weekly instillations to Feb 2027.

@kgborlando, welcome. You may be interested in this related discussion:
- Gem/Doce (gemcitabine + docetaxel): What side effects did you have?https://connect.mayoclinic.org/discussion/side-effects-with-gemdoce-treatments/

How are you doing?