@csrb7007 to my knowledge, a vascular dementia requires evidence of at least one small stroke, usually many, not simply atherosclerosis.

I don’t mean to sound dismissive. Atherosclerosis is a whole body disease, including blood vessels in the brain. My thoughts would be to treat atherosclerosis (cholesterol mostly) as aggressively as her dementia warrants. In other words, the more functional she is, the more aggressive the treatment would be. Lifestyle changes are likely to do no harm, but every medication is a chemical with side effects and such. With the information in front of me, the biggest issue is the 85% LAD lesion. I would leave treatment of this to her cardiologist and PCP.

Another good specialist to have in your arsenal is a palliative care doctor. They are very good at balancing the pros and cons of various treatments. Some have the belief that these doctors only treat hospice or patients nearing end of life. Nothing could be further from the truth. They are available to anyone and are well versed in a multitude of areas that you might find helpful. Consider googling to find out more.