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“Long COVID's brain fog finally has a biological explanation:
Dopamine loss

For years, long COVID has been defined almost entirely by what patients report feeling: fatigue, brain fog, memory lapses, a loss of motivation that won't lift.

Recent brain imaging researcn links persistent long COVID neurological symptoms to measurable reductions in dopamine-releasing nerve terminals in the brain.
A study published in eBioMedicine by researchers at the Centre for Addiction and Mental Health (CAMH) used PET scans to compare adults with long COVID to healthy control participants. Patients with long COVID showed a 16% to 20% reduction in VMAT2 (a marker for dopamine nerve terminal density) across key regions of the striatum. *
This offers objective, biological evidence that long COVID neuropsychiatric symptoms are rooted in physical changes in the brain rather than being psychological.”

What’s interesting too , is this is exactly what happens in Parkinson’s disease.