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Anyone on Pluvicto? Looking for a support team

Prostate Cancer | Last Active: 20 hours ago | Replies (86)

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Profile picture for gwbell3 @gwbell3

Metastatic prostate cancer. Have been doing hormone therapy (Abiraterone and Relugolix) for the past year, but after significant PSA decline, numbers have started jumping up again. Recently recommended by my oncologist to start Pluvicto. I'm still trying to decide if I really want to make that jump. Does anyone else on here, taking Pluvicto, have COPD and a heart condition? If so, how have your treatments gone?

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Replies to "Metastatic prostate cancer. Have been doing hormone therapy (Abiraterone and Relugolix) for the past year, but..."

@gwbell3
If your PSA is rising while you are on double therapy, that usually means you Have become castrate resistant. That happened to me six years ago with just ADT.

You could ask your doctor to switch you from abiraterone To one of The lutamides. Darolutamide Has the least side effects and would be preferred if you have a choice. Abiraterone or Enzalutamide Also could work. They’ve been shown to be effective to keep the PSA down when abiraterone Treatment fails.

You want a PSMA PET scan, however, to see if there are any metastasis that are visible. If there are they can frequently be zapped with SBRT Radiation.

A couple of different things to talk with your doctor about.

@gwbell3, did you decide to start Pluvicto? Did your oncologist address your concerns about treatment and living with other chronic conditions like COPD and a heart condition?