@jeffmarc Fabulous summary! And to my knowledge, about as accurate as one can get. I too had genetic testing done when first diagnosed 8-years ago. It took almost 6-months to get the results, but I was told by that specialty group, that I too, lacked the two BRCA-1 and -2 mutations of genetically induced prostate cancer, and that my specific case, was strictly a "lifestyle disease" (i.e., I did not "inherit" the disease, nor could I pass it on to male children). My radiation oncologist later concurred with that genetic assessment, and notably, my own father died at age 80 of bladder cancer (never having had prostate issues).

As for the incidence of secondary cancers occurring to non-target tissues from radiation treatments later in life, again, my oncologist fully agreed with what's been said here. He stated that the reported incidence of such "secondary" cancers, was well below 3%, and that the vast majority of that 3% did not occur for 10 or more years. For what its worth, he had also stated at one point, that the radiation level of IMRT (external beam radiation), was roughly twice the strength of an average x-ray.