@jamesthom101 81 year old male, active, healthy, no meds prior to Mac. Had 2 large cavities. Azith, Ethamb, and IV Amikacin for 4 months and cavities closed significantly. No side effects from Amikacin. They should be checking your blood weekly for any abnormalities. I administered it at home with no problems. Nurse came weekly and changed dressing on Pic line and drew blood. Now on Arikayce and will do CT in Dec. No side effects so far. Good luck.