Edema/Lymphedema- My story: I had 45 IMRT sessions last fall and ADT Rx ( orgovyx and nubeqa) started JUly 11, 2025. Was sailing along ok til JUne of 2026 when I hit my ankle on some furniture and noticed some swelling and it didn resolve quickly like in the past. In fact it became worse but still only in rt leg and manageable I guess. Then late in July, I had Prolia injection and a few weeks after I noticed left leg swelling as well. Now I have edema ( lymphedema?) in both legs/feet. And some wt gain ( now around 250 lbs where normal is 215 or so) SO researched side effects of ADT and Prolia and guess what ? both cause edema and after my 45 IMRT last fall, I think my pelvic lymph nodes are unable to flush the lymph fluids from legs efficiently and it has affected my life in a negative way. I can still bike and walk but it is uncomfortable.

I am hoping it resolves gradually over time but got insurance to buy the compression leggings that massage legs-I was told it does help edema a great deal. ( still waiting on delivery)

I recently wrote here on this site, that I was disappointed my oncology team did not tell me about prolia side effects ( edema and fatigue among other things)..

Anyone else gone thru this BS !?