I have taken 1 Nervive in the morning and 1 Nervive PM at night for a couple of years. It works for me. I have less pain, tingling, burning, and numbness in my feet. My husband tried it and said it did nothing for him; however, with all supplements, there is not an instant effectiveness. They need to be taken for at least 6 months (in my experience). When my feet do feel tingly and burning mostly at night, I wear compression socks to bed but they are not your usually compressions socks. They only go up the ankle and the toes are open. They gently squeeze your feet and by morning, my feet feel great.