@joaf37 I asked my husband this question- we both had to take a trip down memory lane to get the answer, it's been a few years, LOL. He says he thinks the amlodipine was replaced by lisinopril. Figuring that the amlodipine is prescribed to lower blood pressure ( and it was in my husband's case), if this medication is discontinued due to its side effects, the substitute would likely be another blood pressure medication. This could be chosen from a number of medications, depending on the patient's needs, other conditions, medications he/she is already taking. The provider might add another blood pressure medication as a substitute for the amlodipine- could be another calcium channel blocker like diltiazem, an ACE inhibitor or ARB ( examples lisinopril or Valsartan), a diuretic, or a beta blocker. Or the provider might increase the dose of another pressure med that the patient is already taking when the amlodipine goes away. As you can see, there are many options, and are best discussed with the subscriber!