@stragale The on ADT until you die is often the case because most prostate cancer patients are elderly and die of something else. I took it as an indication that the disease was metastatic, so no 4 to 24 month and then done. In your case if the drugs stop working the usual switch is to a 2nd generation lutamide (Nubeqa, Erleada, or Xtandi). They will usually work when Abiraterone stops. Also 24 months to castrate resistant is old. Most patients go many years more now with the new lutamides. After that there are the other treatments mentioned.