@alxlo1 These are two of the topics that came to mind. DLI or reducing the immunosuppressants if there is the possibility of boosting the impact of the transplant…if that would help with your situation. Keeping in mind I’m not a doctor so I may be way off base in this case. I know both ‘treatments’ have helped, personally in my own experience, and from shared information with conversations I’ve had with my transplant doctor and fellow BMT people.

It’s obviously important to guard against graft vs host disease. But we do need the benefits of this side effect of an allogenic stem cell transplant. Cyclosporin has been added to transplant protocol to help reduce the possibility of more aggressive side effects of gvhd. There is a fine line between ‘finding the sweet spot’ with too much suppression or just the right amount. Since no two people are alike it can take some tweaking. This was from the discussion I’ve had with my own transplant doctor at Mayo. Wishing you well on your journey. Will you keep me updated please?