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@lchop
I was on duloxitine (60mg) for many years, along with trazadone and mirtazipine. Did nothing for the pain. Per my doctor, pain will trump any medication like this. The trazadone does help to sleep, as does mirtazipine, which acts as an appetite stimulant. I've lost about 20 lbs since the pain makes me really nauseous. Unfortunately, my chronic lumbar pain makes it impossible to get a good solid night sleep. I've do take 15mg of tramadol which takes the edge off somewhat, but it's considered a lower type of narcotic. Gabapentin 300mg 3x, made me quite loopy during the day so that was stopped. Good luck to you, as I understand the total frustration.

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Replies to "@lchop I was on duloxitine (60mg) for many years, along with trazadone and mirtazipine. Did nothing..."

@karentheo Tramadol made me constipated so I had to take Citrucel nightly .
It was not really helping with my stenosis pain at the low dose I was on because of the GI effects for me.
So far the Gabapentin and duloxetine are helping very much.
I take care when I take it and not drive if I feel too sleepy upon first taking it.
That settles down after a while and isn’t so sedative thank goodness. I’m glad like have my husband as my driver😊.

@karentheo Thanks, I have been on all those still weaning off Gabapentin down to 300mg still on 100mg Trazodone great for sleep but sedated all morning. Feel sometimes we are getting fobbed off and its almost impossible to see a GP. Worrying about going to bed has made me anxious and depressed knowing the sort of night I am going to have. How can I get Tramodol ? Told by GP I cant have an opiod whilst on Trazodone and Gaba. But I need a good pain killer. These others do not really kill the pain at night.