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Tymlos Side effects

Osteoporosis & Bone Health | Last Active: 2 hours ago | Replies (74)

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Profile picture for WilWeten @wilweten

@willowmena These rats got 3 times the amount per kilo that humans get and also got that from the beginning of their lives and onwards. So, that's a massive overdose for a long time...

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Replies to "@willowmena These rats got 3 times the amount per kilo that humans get and also got..."

@wilweten but I question the data and how humans respond to the maximum dose of 80 mcg. When I looked at results from clinical trials it gave data on many conditions that participants experienced, none of it actually an outcome of the medication apparently, but I don't recall seeing meaningful data on bone cancer. As for the rats, even at lower doses, a certain percentage of them developed bone cancer, just a lower percentage.

@wilweten Taken from online research: During drug testing, Tymlos (abaloparatide) caused a dose-dependent increase in a rare type of bone cancer called osteosarcoma in both male and female rats at exposures 4 to 28 times human levels. "It remains unknown if this risk applies to humans"