Thank you so much for your replies. I figured I either had diverticulitis or IBS. My doctor told me if I have to go off the Actemra, she could no longer do anything for me. I can't take Prednisone because I developed Glaucoma from being on it for PMR then 6 months remission. I was hit with GCA after 6 months of remission from the PMR.. I started on prednisone then my doctor put me on Actemra and weaned me off prednisone. I have 10 more infusions to go before she takes me off of Actemra. I can't take Prednisone because I developed Glaucoma from being on it for PMR then 6 months remission. I feel I should ride it out the best I can. I haven't mentioned to her my problem. I am 85 and also developed stage 3 CKD. Wether this is from the Actemra I don't know. Ahhhh, the joys of growing old!!