This is my third round of treatments for M. abcessus and in two of the three IV antibiotics were given via PICC line. I currently am using a PICC and actually prefer it because, for me, the nausea is much less. There is the inconvenience of having to keep track of the medications I use here at home but I figured out a routine. I run the first one during my morning Huff Vest routine and the other with the evening so the time commitment is less. The technology for the home IVs is super easy and once you are used to handling the lines there is no stress . For me the trade off to have fewer side affects is a simple one