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← Return to getting back to normal after ADT
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getting back to normal after ADT
Prostate Cancer | Last Active: 8 minutes ago | Replies (57)Comment receiving replies
@jeffmarc My first blood work six weeks post treatment (18 months Orgovyx) showed PSA still <.01 but testosterone has risen from <10 to 48. Regretfully, I don't have pre-treatment testosterone number. I still have plenty of hot flashes but am starting to feel a bit more "normal."
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@jime51
Sounds like a good start. Because you were on it 18 months, it might take a little longer to come back, but the below study was almost a year and half the people got it back to a minimum required level in 86 days. Give it a little more time and you’re going to feel a lot better?.
In the HERO study, relugolix demonstrated sustained testosterone suppression superior to that of leuprolide acetate (97% vs 89%; difference 7.9% [95% confidence interval, 4.1–12%; p < 0.001]).
Men (N = 934) were randomized (2:1) to receive relugolix 120 mg orally daily or leuprolide acetate injections every 12 wk for 48 wk.
Overall, 74 of the 137 men in the relugolix cohort recovered to testosterone >280 ng/dl, with a median time to recovery of 86.0 d (95% CI, 65.0–92.0), versus two of the 47 men in the leuprolide cohort, with a median time to recovery of 112.0 d
https://www.sciencedirect.com/science/article/pii/S2588931123002900