Connect
← Return to PSA "undetectible" for amost a year
Discussion
PSA "undetectible" for amost a year
Prostate Cancer | Last Active: 6 hours ago | Replies (38)Comment receiving replies
@johnfinch
Actually, according to the American Society of clinical oncology, you should’ve had Salvage radiation when your PSA hit .2. Waiting as long as you are, could make it worse. Here’s their specific recommendation for those that have had a prostatectomy.
From Ascopubs about what PSA to do salvage radiation.
≤0.2 ng/mL:
Starting at this level maximizes disease control and long-term survival. Patients treated at PSA < 0.2 ng/mL achieve higher rates of undetectable post-SRT PSA (56-70%) and improved 5-year progression-free survival (62.7-75%).
Delaying SRT beyond PSA ≥0.25 ng/mL increases mortality risk by ~50%.
0.2–0.5 ng/mL:
Still effective, particularly for patients with low-risk features (e.g., Gleason ≤7, slow PSA doubling time). The Journal of Clinical Oncology recommends SRT before PSA exceeds 0.25 ng/mL to preserve curative potential.
0.5–1.0 ng/mL:
Salvage radiation remains beneficial but may require combining with androgen deprivation therapy (ADT) for higher-risk cases.
This article discusses the above;
https://ascopost.com/news/march-2023/psa-level-at-time-of-salvage-radiation-therapy-after-radical-prostatectomy-and-risk-of-all-cause-mortality/
Replies to "@johnfinch Actually, according to the American Society of clinical oncology, you should’ve had Salvage radiation when..."
@jeffmarc
Thanks for responding. At .041 my current PSA number is significantly less than .2. If it gets as high as .2 I hope my urologist recommends radiation.
Connect
@jeffmarc It kind of feels like you're rushing to respond to things and not actually reading what people write. You wrote this alarmist reply to @johnfinch but his PSA is way below 0.2 -- he says it's 0.041 now, which is 5x lower than that threshold.
Also, that link you shared in your reply does not say all of those things you say it does. Do you have a correct link to a source for this claim:
"≤0.2 ng/mL: Starting at this level maximizes disease control and long-term survival. Patients treated at PSA < 0.2 ng/mL achieve higher rates of undetectable post-SRT PSA (56-70%) and improved 5-year progression-free survival (62.7-75%). "? I don't disagree with the sentiment but I cannot find that quote or those exact numbers in any source.
You share a lot of great info here but you've been missing and misunderstanding a fair bit of what people are writing lately, hope everything is ok on your end.