Hi @cole5055

That’s a great PSA drop! Here’s my history. I’m not sure how it will format here but you’ll be able to pick out the relevant dates and values. (But the answer is that it took about 2.5 years to hit the nadir of 0.59.)

PSA/Procedure History
17-Mar-2021 5.9
13-Apr-2021 Fusion Biopsy Gleason 3+4=7
04-Aug-2021 3.9
16-Sep-2021 4.4
17-Sep-2021 Repeat Biopsy required for NanoKnife Clinical Safety Trial: Gleason 3+4=7.
22-Oct-2021 NanoKnife IRE Procedure Right-Sided Index Lesion
25-Oct-2021 MRI Good ablation zone indicated.
17-Nov-2021 0.84
27-Jan-2022 1.1
21-Apr-2022 0.92
21-Apr-2022 MRI No imaging evidence of recurrence.
22-Apr-2022 Ablation Zone Biopsy No evidence of disease.
25-Jul-2022 0.82
27-Oct-2022 0.72
13-Apr-2023 0.7
08-Nov-2023 0.59
08-Nov-2023 MRI Post ablation change. Stable, no new concerns.
08-May-2024 0.57
03-Dec-2024 0.603
07-Mar-2025 MRI: No imaging evidence of new or recurrent disease.
12-Sep-2025 0.86
03-Mar-2026 0.891
23-Mar-2026 0.978
11-May-2026 MRI: No imaging evidence of new or recurrent disease.

I moved to Spain in 2024 so I’ve lost the PSA lab/assay consistency that I had from Mayo Laboratories. I’ve also been on Dutasteride for decades so all my PSAs need to be doubled for comparison purposes. That means my current PSA is considered to be around 2 and 2.5 is the threshold in Spain for consideration of recurrent or new disease.

I know PSA is only one component, but you must be ecstatic over your drop! Hopefully your side effects have been equally low!