@bythesee5: You have truly been through the wringer with adverse effects. Looking on the bright side here is that individuals who have these tend to remain NED longer with increased survival rates. I know that may sound like a trade-off when you feel miserable from the effects you've had as result of the immunotherapy. May I ask what immunotherapy protocol you had been on and how long the treatment had been before these ir-AEs (immune-related adverse effects) occured?

This can be a complicated issue, however many endocrinologists are knowledgeable in and equipped to handle andrenal insufficiency, although some may tend to focus on other issues such as diabetes or thyroid concerns. Can you explain more about the "cancer connected endocrinologist" and what you mean by their being distand regarding care? For instance, is this specialty on staff at the facility where you treated for the melanoma? If so, can your oncologist intervene to assist with prioritizing your concerns? Which medical professional is providing oversight of your Wegovy?

It's definitely a lot to try to handle on your own and requires medical managment. If you feel you could benefit from greater intervention, would it be difficult to establish care with another recommended endocrinologist in your area who has experience in adrenal insufficiency?