Hello Kay - as to how I got the pseudemonas: I can not say for sure, but this is the sequence: I began the Big 3 in Nov of 2015. My cough however became worse in November and December and I was concerned that it was different from the MAC cough - the mucous was much more and a whitish green... I would cough for a long time to clear my lungs. Finally in mid-December, my doctor ordered a sputum test as she suspected pseudemonas - I had never heard of it and my lung doctor never mentioned it. Test came back positive and I went on Levaquin right away for 10 days, on top of the MAC meds. The Levaquin stopped the coughing within one week - it was amazing. Then by Jan the MAC meds were finally kicking in and I was coughing very little. It is very possible that the pseudemonas came from my hot tub which I had used that fall. I did not get in my hot tub again needless to say and that spring, I had the water tested - it came back positive for pseudemonas but they did not find MAC. The cough with pseudemonas is very different from the MAC cough; much more productive and leaves one coughing a lot when you lie down. I have given my hot tub away. I took the MAC meds for 18 months and except for several bouts of pneumonia, I am not coughing - is the MAC gone?.... I have no idea. Sorry for such a long email and best to you, Pamela