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What is the major difference between pregabalin and gabapentin?
Neuropathy | Last Active: 2 days ago | Replies (90)Comment receiving replies
You wouldn't add it you would replace the GabaPentin with Pregabalin. Wouldn't make sense to take both. It may control things better. Only way to know is try switching.
""generally not recommended. Because both medications belong to the same drug class (gabapentinoids) and work in very similar ways, combining them doubles up on the same mechanism without providing unique benefits, significantly raising the risk of severe side effects.""
Replies to "@dbeshears1 You wouldn't add it you would replace the GabaPentin with Pregabalin. Wouldn't make sense to..."
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@bajjerfan You are absolutely right - thinking back to then, I do recall he offered a “switch” from Gabapentin to Pregabalin, not adding it. But since I was stable on Gabapentin with no complaints for what was 8 years at that time, and he couldn’t explain any improvements I could get from switching, we agreed that switching because some others liked it wasn’t good rationale for me since I was doing fine with Gabapentin. Gabapentin is basically free in my plan as well, so paying $$$ for no known improvement opportunities for me (and possible weight gain) wasn’t very sensible for me. If Gabapentin stopped working or started giving me side effects after these 10 years I’ve now been on it, I would certainly consider switching.