68 year old, Prostate cancer onset at 55.
2013 - 2014 PSA rose from <4 to >12. MRIs, Scans, and Biopsy showed multiple lesions 4+3=7 and suspected spread to bladder neck.
Radical Prostatectomy 2015. PSA rising so 39 EBRT with Lupron in 2016.
PSA rising again 2021 see chart.
PSMAPetScan 2023 found metastasis on Left iliac, treated with proton SBRT. PSA still rising PSMAPETScan found metastasis on Right iliac, treated with proton beam SBRT.
PSA till rising PSMAPetScan found ABDOMEN/PELVIS: Prostatectomy without suspicious tracer activity at the vesicourethral anastomosis. Tiny new tracer avid left periaortic retroperitoneal node (image 124), aortocaval lymph node SUV max 6.7 (image 136), and right obturator lymph node SUV max 7.4 (image 152). Additional minimally avid foci anterior to the right S1 segment on the prior study is less conspicuous on the current study. Left hepatic cyst. Cholelithiasis. Stable unenhanced appearance of the remaining solid abdominal organs.
MUSCULOSKELETAL: No suspicious radiotracer activity. Previous faint tracer uptake within the left posterior 6th rib in the right iliac bone are less conspicuous.
IMPRESSION
1. Few tiny retroperitoneal and pelvic lymph nodes with demonstrate mild tracer uptake suspicious for nodalmetastases. Key images saved.
2. No findings for metastatic disease elsewhere.
CO said he would not want to zap those as previously mentioned.
My experience with Lupron while getting EBRT: unbearable hot flashes, not able to sleep, muscle loss very quickly, cramps, stomach distress. They put me on trazadone which made previous minor tinnitus major and still nearly unbearable.
This is the short story!
Meeting with the new CO Thursday, will proably go back to Mayo MN for 2nd. I live in Minneapolis, MN in the winter and northern MN (Lake Vermilion) in summer.
@briang1958
Definitely go to Mayo in Minnesota and speak to Dr. Heath. She is a really great oncologist that speaks at many meetings and is really loved by her patients. You would have the best options for treatment from her.
You might want to ask about using estradiol instead of ADT. That can avoid a lot of the side effects you had but also work to reduce your testosterone. It definitely sounds like you need an ARPI, Darolutamide would be the best.
Get yourself a really good oncologist, One that specializes in prostate cancer. You have a very advanced case and you don’t want to encounter the pain that prostate cancer can cause if left untreated.