@sunterrace Welcome to Mayo Clinic Connect! You are increasing your meds on your own which is not really safe but I can understand since your doctor is out of town for a month. Does he have another doctor in his office that you can call and get an appointment? Or have you thought about going to a comprehensive medical center? They are usually located near large cities. Or a university medical center. The doctors are frequently involved in some research so know more about these “new-ish” diseases. Just call one and ask to be connected with the gastroenterology department. Explain your problem and ask if you could get an appointment. Even if it is a drive your health is worth it. My husband did just that. He called the university medical center about 1 hour away and explained that I was in the ER and that no one had a clue. We were able to get an appointment and the university hospital was able to tell the ER docs in the local hospital how to treat me until i could get to the university.