@ipg I am 70 too. I was rejected by an endocrinologist and gynicologist for HRT as well. I searched for a private practice gynecologist who, in tandem with my cardiologist, after careful evaluation, cleared me for HRT. I had a total hysterectomy at age 34, and I was on Premarin until age 50 when WHI came up with a warning about stroke. Transdermal estradiol works differently from oral once and has few to no side effects. I cannot take bisphosphonates due to my dental implants issue, so HRT is one to back up gains from Forteo for me.