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Neuropathy treatments: How to avoid scams?

Neuropathy | Last Active: 2 hours ago | Replies (875)

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Profile picture for John, Volunteer Mentor @johnbishop

@jakedduck1 Interesting question - I've often thought about mine in relation to how it was progressing when I started paying attention back in 2016 and started taking supplements including R-ALA. My only gauge is that it hasn't gotten into my upper legs yet with the same feeling as my feet and toes. I think the only real way to tell is if you have a skin punch biopsy when you are diagnosed and then probably get another one sometime later to actually count the number of dead nerves. I never had one when I was diagnosed by a nerve conduction study along with exam and labs so not sure it would even help me learn if it's progressing now.

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Replies to "@jakedduck1 Interesting question - I've often thought about mine in relation to how it was progressing..."

@johnbishop
Out of curiosity I think you said you were diagnosed with SFN? SFN is diagnosed by skin punch biopsy and large fibre is detected by EMG and or nerve conduction study. Or so I was told but I was diagnosed with large fibre sensorimotor polyneuropathy not too long ago with both emg and nerve conduction. I wander if that explains the numbness, balance problems as those are more large fibre and small is known for pain. I alway wandered why I didnt have pain but I initally wasnt told I had large fibre but just the blanket term neuropathy. I am curious as I know a person can have both small and large but always wandered if once diagnosed with large they would even bother to check for small? I checked on google and it seems to correleate:

“Standard EMG and NCS tests only evaluate large nerve fibers and large motor or sensory units. Because small unmyelinated or thinly myelinated fibers do not significantly impact large muscle or nerve electrical conduction profiles measured by these needles and surface electrodes, an SFN patient typically has a completely normal EMG/NCS result“