@pkeelan56 Are you saying that Mayo said that Rituxan is the only treatment for anti-MAG neuropathy? That would shock me. Checkout: Brukinsa (newest BTK Inhibitor). You can Google the results... but I think Brukinsa is effective (eliminating IgM impact on myelin-nerve lining) in 71.4% of cases with the effects evident in an average of 4.6 months. Brukinsa has far fewer (common) side effects than Rituxam but Rituxam is probably used in more virulent (higher IgM) cases than Brukinsa.

My Anti-MAG antibodies (AMA) test was positive (reading "1531") and one-month after starting my Brukinsa, my AMA reading was <900 (normal range 0-999). Having said that, my neuropathy pain (24/7 foot numbness) was a bit worse. Apparently, that is to be expected as the drug attacks the nerve lining IgM clonal cells. When the die, the dead cells have to be removed and filtered through the kidneys and that takes time. I'm waiting patiently for the 4-5 month positive outcome.