@carolgrandma I am experiencing similar effects that I can only attribute to Reclast - a week of flu like symptoms followed by constant pain in my joints from head to toe. Taking ibuprofen or acetaminophen has little to no effect. My doctor says this will subside over time, but I will refuse this drug in the future due to the negative impact it is having on the quality of my day to day life. I have also had increased hair loss well beyond what is normal for me. Had I known this would be my daily battle before agreeing to the infusion, I would have refused it. Best wishes for all who are experiencing negative effects.