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Lupron or Not at 76?

Prostate Cancer | Last Active: 6 hours ago | Replies (53)

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@tbgb50 Lupron creates a flare (higher testosterone) for the first 2-3 weeks. It takes 4-6 weeks to drop testosterone to castrate levels. It also takes 3 or more months after the expiration of the shot to recover testosterone. A 3-month shot will give you about 5 months at castrate levels (or more if your testosterone does not recover). Failure to recover testosterone is highly correlated to age (especially 80+) and length of time at castrate levels. A much higher percentage recover testosterone at less than 70% of pretreatment levels.

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Replies to "@tbgb50 Lupron creates a flare (higher testosterone) for the first 2-3 weeks. It takes 4-6 weeks..."

@jim18

I was 82 when treatment started and 83 when it ended. Side effects were awful and it took about 10 months to even start recover from side effects and a testosterone rise to 111. Side effects did not stop until I started testosterone replacement treatment just 2 weeks ago.

@jim18 Thanks for the information - especially regarding age since that is my dilemma. The oncologist said my testosterone recovery = the length of treatments. So based on their recommendation a total of 4 years. He also said I may not recover much since I will be 80 then. This get worse and worse as far as making a decision but at least I have more information. I know there is no guarantee but I'm reaching the point where it is Orgovyx for a short time or changing urologist if I get push back.