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Lupron or Not at 76?

Prostate Cancer | Last Active: 6 hours ago | Replies (53)

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@pesquallie If Lupron is my only option then I'm going to ask for no more than a 3 month shot. The way the oncologist explained things, the radiation has an 80% success rate for high risk PC and the Lupron adds another 5%. My problem is understanding the 80%. It's an average based on your risk scores but does not consider age. I can't believe people in their 70s have the same success rate as those in their 40s or 50s.

Seems like high risk low reward at my age (76) so the 3 month shot can hopefully allow me to bail if it is too much for me and still recover.

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Replies to "@pesquallie If Lupron is my only option then I'm going to ask for no more than..."

@tbgb50 Lupron creates a flare (higher testosterone) for the first 2-3 weeks. It takes 4-6 weeks to drop testosterone to castrate levels. It also takes 3 or more months after the expiration of the shot to recover testosterone. A 3-month shot will give you about 5 months at castrate levels (or more if your testosterone does not recover). Failure to recover testosterone is highly correlated to age (especially 80+) and length of time at castrate levels. A much higher percentage recover testosterone at less than 70% of pretreatment levels.