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New research on length of ADT therapy for patients with RT
Prostate Cancer | Last Active: 9 hours ago | Replies (41)Comment receiving replies
@heavyphil I hear you Phil. I wasn't going to do it after consulting with Dr Scholz and he felt I didn't need ADT. He said it would only add 5-8% to my treatment success. This was after Top docs at COE's Univ ofPenn & Fox Chase both recommended ADT because of high PSA (both going by NIH guidelines). What convinced me to do it was when I consulted with Dr Chang and told him what Dr Scholz said he put things in perspective and said in the prostate treatment world 8% is a lot! His thoughts were my treatment plan of HDR Brachy and SBRT is a very aggressive treatment and probably don't need ADT but a short course 4-6 months would still be beneficial.
Replies to "@heavyphil I hear you Phil. I wasn't going to do it after consulting with Dr Scholz..."
@copyman I always look at the inverse for these. If your treatment has an 80% chance of 10 years no recurrence going to 88% is an additional 10%. However, looked at from chance of a recurrence the 20% went down to 12% for a 40% decrease. This can be applied to recurrence, metastases, death or any other success statistic available. Sometimes even these numbers get very small especially with extended (> 1 year) ADT for localized prostate cancer when the total effect on the body is considered (all causes mortality).
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@copyman Yes - 8% is a whole lot…many poo-poo a single digit advantage but if you were investing your $$, would you go for the 10% return or the 18% return?
True, the higher return comes with some risk (SE’s), but they are usually not permanent and there are tried and true ways to overcome them.
I think your RT and ADT regimen will totally do the job…Best,
Phil