← Return to Lupron or Not at 76?

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Lupron or Not at 76?

Prostate Cancer | Last Active: 6 hours ago | Replies (53)

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Profile picture for brianjarvis @brianjarvis

Regarding your biopsy in 2022, was that an MRI-guided biopsy?

My oldest brother is 1 year into his 2 years of Eligard. He should expect 50% more time (= +1 year) of recovery = 3 years total. True, the older the age, the higher the risk of testosterone not recovering.

Your Gleason 9 (is that a 5+4 or a 4+5?) is very high risk disease, with a high risk of metastasis. You mention “… another 5% with the Lupron” - however with very high-risk disease, I would not want to under-treat it. (I would get an ArteraAI prostate test to see if ADT would be beneficial.)

In your MRI and biopsy reports, is there any mention of cribriform pattern, extracapsular extension, seminal vesicle invasion, perineural invasion or intraductal carcinoma? (If not, that’s good.)

If it was a Gleason 8 (high risk disease), I might go with just 1 year of Lupron; but with very high risk disease (Gleason 9), I’d go with 2 years.

Ultimately, it’s your call; you’re the one that has to live with the outcome, one way or the other.

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Replies to "Regarding your biopsy in 2022, was that an MRI-guided biopsy? My oldest brother is 1 year..."

@brianjarvis
Thanks for the advice.

I did not know about the ArteraAI prostate test this so will ask for this.

"In your MRI and biopsy reports, is there any mention of cribriform pattern, extracapsular extension, seminal vesicle invasion, perineural invasion or intraductal carcinoma? (If not, that’s good.)"

I checked the MRI, PET scan and biopsy and none of these are mentioned at all.

I'm probably going to start the Lupron (or Orgovyx) and decide at the 1 year mark whether is is worth continuing.