@eparnold0219
I had to start a fast taper because of a subsequent SMM diagnosis. I have had mild to moderate pain at the start of each decrease which subsided or leveled after a few days. I was doing 2.5mg decreases every 10 days until I reached 10mg, then 0.5mg every 4 days until I reached 5mg. My plan now is for 0.5mg decrease every 7 days, but I will only do another decrease when my body adjusts to the new dose. My hematologist-oncologist needs me to be at or under 5mg prednisone for my next blood work in order to better assess my SMM risk factor. I take the LDN about two hours before bed and it helps me sleep.