@dragonflylady
I also have IgA Nephropathy. As jlferro1 stated in his comprehensive description of the disease, it often becomes worse slowly over the years, but it can hold steady. Like your brother, my initial finding was protein in the urine. Lupus was suspected, but after many blood tests and a kidney biopsy, I was diagnosed with IgA Nephropathy, and I was told it was an autoimmune disease. I, too, am of European descent (actually, I am first generation). My diagnosis was nearly 40 years ago, and I am still here, even though my prognosis was not positive!

My nephrologist also has started me on Farxiga, which is indicated to be protective of the kidneys. I also am on a remote blood pressure monitor, since controlling blood pressure is important in CKD. I stay well hydrated, NEVER take an NSAID (such as Advil, Ibuprofen, or Aleve) and am careful to limit (not eliminate) foods found to be harmful to the diseased kidneys; that includes red meat, bananas, tomatoes, avocados, etc.

Through the years, I have developed some heart issues (currently have a pacemaker), and I learned that heart problems very much affect the kidneys. So, tell your brother to see his cardiologist and take good care of his heart.

I am also on monthly infusions. However, they are not due to my IgA Nephropathy. They are not to suppress my immune system, but to increase it. You noticed that I use the prefix "CLL" because I was diagnosed with that a couple of years ago. Since leukemia often depresses the immune system leading to multiple infections, my infusion are to build it up.

I read the anxiety in your words, and I understand! When I was told I had a kidney disease - I pictured dialysis, transplantation, etc. I was devastated! Of course, those issues could come to pass. However, they also might NOT come to pass! You are wise to educate yourself (and your brother) and ask questions. Being informed helps. Follow the nephrologist's advice and know that it is possible to live many years with this disease. Wishing you all the best!